Papi mixidine is a combination of miconazole hitrate and chlorhexidine gluconate that helps provide relief fungal infection such as ringworm, and superficial skin infections caused by yeast and bacteria. DIRECTION for USE: wet your pet with thoroughly with luke warm water let lather remain for few minutes. Apply Mixidine shampoo all over your pets body with heavy leather concentrating on the heavy affected area.Avoid contact with eyes,nose,inner ears and mouth. Rinse throughly and dry clean towel